Studies on the Relation of Tetanus Bacilli in the Digestive Tract to Tetanus Antitoxin in the Blood

The Immunity Produced by the Growth of Tetanus Bacilli in the Digestive Tract

1. A method for the production of tetanus by the injection of a fixed number of spores is described together with the tests made in selecting animals for experimental work. 2. Guinea pigs fed a single serological type of tetanus bacilli will, after 6 months, show considerable amounts of antitoxin in their sera and will manifest immunity to the type fed. To other types they are just as susceptib...

The Tetanus Bacillus as an Intestinal Saprophyte in Man

1. The only reliable method that can be used for the detection of tetanus bacilli is the culturing of the suspected material, the isolation of tetanus-like organisms and the demonstration that the pure cultures form a spasm-producing toxin that is neutralized by tetanus antitoxin. 2. Using this method we have demonstrated tetanus bacilli in 34.7 per cent of stools from 78 individuals in Peking....

Evolution in the Production and control of Equine Tetanus Antitoxin During the last 3 decades in Iran.

بررسی وضعیت ایمنی علیه کزاز در افراد بالای 50 سال در کاشان

Ojectives: Tetanus is a neurologic disorder which occurs as sporadic cases in people with incomplete vaccination course.The most tetanus patients are people over 60 years of age.It is a important disease in elderly patients because of risk of severe forms and high rate of morbidity and mortality This study was conducted to evaluate tetanus immunity in 50 years of age and older people in kashan-...

ایجاد یک روش نوین آزمایشگاهی الایزا توبی (ToBi Assay) برای تعیین پوتنسی واکسن بومی توکسوییدی کزاز درایران

Background: One of the major uses of large number of laboratory animals in manufacturing the vaccines is the quality control testing of vaccines, particularly potency testing of vaccines containing the tetanus toxoids by either lethal challenge or serum neutralization tests. Recently, because of various difficulties to obtain quality laboratory animals and in adequate environmental conditions, ...